Article
Strong asymmetric mutation bias in endosymbiont genomes coincide with loss of genes for replication restart pathways.
Molecular biology and evolution - 1 May 2006
Klasson Lisa, Andersson Siv G E
Abstract excerpt
A large majority of bacterial genomes show strand asymmetry, such that G and T preferentially accumulate on the leading strand. The mechanisms are unknown, but cytosine deaminations are thought to play an important role. Here, we have examined DNA strand asymmetry in three strains of the aphid endosymbiont Buchnera aphidicola. These are phylogenetically related, have similar genomic GC contents, and conserved...
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