Article
Angiotensin I-converting enzyme genotypes and angiotensin II receptors. Response to therapy.
Hypertension (Dallas, Tex. : 1979) - 1 Jul 1996
Dieguez-Lucena J L, Aranda-Lara P, Ruiz-Galdón M, García-Villanova J, Morell-Ocaña M, Reyes-Engel A
Abstract excerpt
In the present study, we studied angiotensin II type 1 (AT1) and type 2 (AT2) receptor messengers by quantitative reverse transcriptase-polymerase chain reaction. We examined peripheral blood mononuclear cells from 30 healthy subjects and 50 subjects with primary hypertension, in whom angiotensin I-converting enzyme genotype was determined, before and after 15 days of treatment with different antihypertensive...
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