Article
Renin-angiotensin system gene polymorphisms influence blood pressure and the response to angiotensin converting enzyme inhibition.
Journal of hypertension - 1 Dec 1995
Hingorani A D, Jia H, Stevens P A, Hopper R, Dickerson J E, Brown M J
Abstract excerpt
OBJECTIVES: To investigate the relationship between polymorphisms in the angiotensin converting enzyme (ACE), angiotensinogen (AGT) and type 1 angiotensin-II (AT1R) genes and (1) quantitative variations in blood pressure and (2) the blood pressure response to ACE inhibition in a hypertensive cohort. DESIGN AND METHODS: We administered monotherapy with ACE inhibitors to 125 previously untreated essential...
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