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Article

Genetic variant of the Renin-Angiotensin system and diabetes influences blood pressure response to Angiotensin receptor blockers.

Diabetes care - 1 Aug 2009

Konoshita Tadashi, Kato Norihiro, Fuchs Sébastien, Mizuno Shinichi, Aoyama Chikako, Motomura Makoto, Makino Yasukazu, Wakahara Shigeyuki, Inoki Isao, Miyamori Isamu, Pinet Florence

Abstract excerpt

OBJECTIVE Recent studies have proven the favorable effects of angiotensin receptor blockers (ARBs) on cardiovascular and renal disorders. However, determinants of the response to ARBs remain unclear. We substantiated the hypothesis that genetic variants of the renin-angiotensin system (RAS) have significant impacts on the response to ARBs. RESEARCH DESIGN AND METHODS Subjects comprised 231 consecutively enrolled...

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Identifiers

PMID: 19509012
DOI: 10.2337/dc09-0348
PMCID: PMC2713645

Genes

REN
ACE

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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