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SCM-198 ameliorates the quality of postovulatory and maternally aged oocytes by reducing oxidative stress

31 Aug 2024

Abstract excerpt

Oocyte aging is a key constraint on oocyte quality, leading to fertilization failure and abnormal embryonic development. In addition, it is likely to generate unfavorable assisted reproductive technology (ART) outcomes. SCM-198, a synthetic form of leonurine, was found to rescue the rate of oocyte fragmentation caused by postovulatory aging. Therefore, the aim of this study was to conduct a more in-depth...

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PMID: 39217393
DOI: 10.1186/s13048-024-01504-2

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