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Article

Effect of maternal age and conditions of fertilization on programmed cell death during murine preimplantation embryo development

1 Feb 1998

Abstract excerpt

One of the major morphological anomalies observed in many human pre-embryos is extensive cellular fragmentation. Previously we confirmed that embryo fragmentation seemed to be associated with the activation of programmed cell death (PCD). The purpose of our experiments was to establish a rate for murine embryo fragmentation in vivo after hormonal stimulation in young versus older females and to compare it with...

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PMID: 9542971
DOI: 10.1093/molehr/4.2.139

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