Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of mutation and growth rates on patterns of microsatellite instability.

The American journal of pathology - 1 Jun 1996

Li Z H, Aaltonen L A, Shu Q, Srivastava S, Grizzle W E, Shibata D

Abstract excerpt

The detection of somatic microsatellite (MS) alterations in tumors is often interpreted as a sign of underlying genomic instability. However, it is unclear why the proportions of altered MS loci vary between different mutator phenotype tumors. We present a simple mathematical analysis that can ac...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Division
Share to Cell Transformation, Neoplastic
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair

Share to Mice, Inbred BALB C

Share to Mutation

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 8669462
PMCID: PMC1861626

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8669462-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Effects of mutation and growth rates on patterns of microsatellite instability.PMID 8669462Read ↗

Somatic microsatellite mutations as molecular tumor clocks.Semantic proximity Read ↗

Multiple mutations in human cancers.Semantic proximity Read ↗

Most low-level microsatellite instability in colorectal cancers can be explained without an elevated slippage rate.Semantic proximity Read ↗

Mutator mutations enhance tumorigenic efficiency across fitness landscapes.Semantic proximity Read ↗

Volatility of Mutator Phenotypes at Single Cell Resolution.Semantic proximity Read ↗

Microsatellite instability and its relevance to cutaneous tumorigenesis.Semantic proximity Read ↗

The natural somatic mutation frequency and human carcinogenesis.Semantic proximity Read ↗

Heterogeneity and evolution of DNA mutation rates in microsatellite stable colorectal cancerSemantic proximity Read ↗

Genetic reconstruction of individual colorectal tumor historiesSemantic proximity Read ↗

Estimating mutant microsatellite allele frequencies in somatic cells by small-pool PCR.Semantic proximity Read ↗

Mutation rate and specificity analysis of tetranucleotide microsatellite DNA alleles in somatic human cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.