Article
CCAAT displacement protein competes with multiple transcriptional activators for binding to four sites in the proximal gp91phox promoter.
The Journal of biological chemistry - 26 Jul 1996
Luo W, Skalnik D G
Abstract excerpt
CCAAT displacement protein (CDP) competes with transcriptional activating proteins for binding to each of four elements within the myeloid-specific gp91(phox) promoter. CDP exhibits the strongest affinity for a site centered at -110 base pairs (bp) of the promoter and progressively weaker affinit...
Topics
- Binding Sites
- Binding, Competitive
- DNA-Binding Proteins
- Gene Expression Regulation
- HeLa Cells
- Hematopoietic Stem Cells
- Homeodomain Proteins
- Humans
- Membrane Glycoproteins
- Models, Genetic
- Mutation
- NADPH Oxidase 2
- NADPH Oxidases
- Nuclear Proteins
- Promoter Regions, Genetic
- Protein Binding
- Repressor Proteins
- Transcription Factors