Article
Surfactant protein D gene regulation. Interactions among the conserved CCAAT/enhancer-binding protein elements.
The Journal of biological chemistry - 31 May 2002
He Yanchun, Crouch Erika
Abstract excerpt
Surfactant protein D (SP-D) plays roles in pulmonary host defense and surfactant homeostasis and is increased following acute lung injury. Given the importance of CCAAT/enhancer-binding protein (C/EBP)-binding elements in the systemic acute-phase response and lung development and the expression of C/EBP isoforms by lung epithelial cells, we hypothesized that conserved C/EBP motifs in the near-distal and proximal...
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