Article
SV40 large T antigen interferes with adult myosin heavy chain expression, but not with differentiation of human satellite cells.
Experimental cell research - 15 Jun 1996
Mouly V, Edom F, Decary S, Vicart P, Barbert J P, Butler-Browne G S
Abstract excerpt
The growth of muscle fibers during late development as well as in regeneration following muscle injury is the result of the proliferation and differentiation of satellite cells. However, all human cells, including satellite cells, show a limit in their proliferation. In order to define a cellular system with enhanced proliferative capacity, human satellite cells were transfected with a construct containing large...
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