Article
Isolation and characterization of the Saccharomyces cerevisiae SUT1 gene involved in sterol uptake.
Gene - 7 Nov 1995
Bourot S, Karst F
Abstract excerpt
A new gene (SUT1) of Saccharomyces cerevisiae, implicated in sterol uptake, was isolated from a yeast genomic library constructed in a high-copy-number vector by virtue of conferring resistance to fenpropimorph in medium supplemented with ergosterol. The high expression of SUT1 in sterol auxotrophic mutant strains alleviates the requirement for accessory mutations affecting heme biosynthesis and allows sterol...
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