Article
Lysogenic conversion by a filamentous phage encoding cholera toxin.
Science (New York, N.Y.) - 28 Jun 1996
Waldor M K, Mekalanos J J
Abstract excerpt
Vibrio cholerae, the causative agent of cholera, requires two coordinately regulated factors for full virulence: cholera toxin (CT), a potent enterotoxin, and toxin-coregulated pili (TCP), surface organelles required for intestinal colonization. The structural genes for CT are shown here to be encoded by a filamentous bacteriophage (designated CTXphi), which is related to coliphage M13. The CTXphi genome...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
