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Article

CTXphi infection of Vibrio cholerae requires the tolQRA gene products.

Journal of bacteriology - 1 Mar 2000

Heilpern A J, Waldor M K

Abstract excerpt

CTXphi is a lysogenic filamentous bacteriophage that encodes cholera toxin. Filamentous phages that infect Escherichia coli require both a pilus and the products of tolQRA in order to enter host cells. We have previously shown that toxin-coregulated pilus (TCP), a type IV pilus that is an essential Vibrio cholerae intestinal colonization factor, serves as a receptor for CTXphi. To test whether CTXphi also depends...

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Identifiers

PMID: 10692381
DOI: 10.1128/JB.182.6.1739-1747.2000
PMCID: PMC94473

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