Article
Analysis of basic fibroblast growth factor in rats with inherited retinal degeneration.
FEBS letters - 27 May 1996
McLaren M J, An W, Brown M E, Inana G
Abstract excerpt
In RCS rats, photoreceptors degenerate between postnatal days 20 and 60, secondary to a genetic defect expressed in the neonatal retinal pigmented epithelium (RPE). Previous work has shown delay of the photoreceptor degeneration in this model by intraocular injection of basic fibroblast growth factor (bFGF). Evidence is presented here, from bFGF immunostaining and Northern analysis of bFGF mRNA, for reduced bFGF...
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