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Article

Placental Growth Factor, a Member of the VEGF Family, Contributes to the Development of Choroidal Neovascularization

24 Jun 2003

Abstract excerpt

PURPOSE: VEGF has been shown to be necessary, but not sufficient alone, for the development of subretinal pathologic angiogenesis. In the current study, the influence of placental growth factor (PlGF), a member of the VEGF family, in human and experimental choroidal neovascularization (CNV) was investigated. METHODS: The presence of VEGF family member mRNA was evaluated by RT-PCR in neovascular membranes...

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PMID: 12824270
DOI: 10.1167/iovs.02-1092

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