Article
Kinetics of strain-dependent differential gene expression in oxygen-induced retinopathy in the rat.
Experimental eye research - 1 Oct 2007
van Wijngaarden Peter, Brereton Helen M, Gibbins Ian L, Coster Douglas J, Williams Keryn A
Abstract excerpt
Recent evidence suggests that retinopathy of prematurity, a potentially blinding condition of premature human neonates, has a genetically-determined component. Different inbred strains of rat exhibit differential susceptibility to oxygen-induced retinopathy (OIR), a well-established experimental model of retinopathy of prematurity. To explore the basis for this differential susceptibility, we quantified the...
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