Article
Female germ cells of Drosophila require zygotic ovo and otu product for survival in larvae and pupae respectively.
Mechanisms of development - 1 Feb 1996
Staab S, Steinmann-Zwicky M
Abstract excerpt
Mutations in the genes ovo or otu can cause abnormal proliferation of XX germ cells, which leads to so-called ovarian tumors, or they can lead to the elimination of XX germ cells, such that adult females possess empty ovaries. Males carrying ovo or otu mutations are unaffected. To find out when this sexual dimorphism affects germ cells, we analyzed the requirement of embryos and larvae for zygotic ovo and otu...
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