Article
Sex determination signals control ovo-B transcription in Drosophila melanogaster germ cells.
Genetics - 1 Feb 2002
Andrews Justen, Oliver Brian
Abstract excerpt
Nonautonomous inductive signals from the soma and autonomous signals due to a 2X karyotype determine the sex of Drosophila melanogaster germ cells. These two signals have partially overlapping influences on downstream sex determination genes. The upstream OVO-B transcription factor is required for the viability of 2X germ cells, regardless of sexual identity, and for female germline sexual identity. The influence...
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