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Article

The role of the ovarian tumor locus in Drosophila melanogaster germ line sex determination.

Development (Cambridge, England) - 1 Sept 1993

Pauli D, Oliver B, Mahowald A P

Abstract excerpt

The locus ovarian tumor (otu) is involved in several aspects of oogenesis in Drosophila melanogaster. The possible role of otu in the determination of the sexual identity of germ cells has not been extensively explored. Some otu alleles produce a phenotype known as ovarian tumors: ovarioles are filled with numerous poorly differentiated germ cells. We show that these mutant germ cells have a morphology similar to...

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Identifiers

PMID: 8275850
DOI: 10.1242/dev.119.1.123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The role of the ovarian tumor locus in Drosophila melanogaster germ line sex determination.PMID 8275850Read ↗

Molecular characterization of ovarian tumors in Drosophila.Semantic proximity Read ↗

Evidence for sex transformation of germline cells in ovarian tumor mutants of Drosophila.Semantic proximity Read ↗

Regulatory and functional interactions between ovarian tumor and ovo during Drosophila oogenesis.Semantic proximity Read ↗

Genetic evidence that the ovo locus is involved in Drosophila germ line sex determination.Semantic proximity Read ↗

Expression of the Sex-lethal gene is controlled at multiple levels during Drosophila oogenesis.Semantic proximity Read ↗

Developmental analysis of the ovarian tumor gene during Drosophila oogenesis.Semantic proximity Read ↗

Regulatory and functional interactions between the somatic sex regulatory gene transformer and the germline genes ovo and ovarian tumor.Semantic proximity Read ↗

Female germ cells of Drosophila require zygotic ovo and otu product for survival in larvae and pupae respectively.Semantic proximity Read ↗

Structure and expression of hybrid dysgenesis-induced alleles of the ovarian tumor (otu) gene in Drosophila melanogaster.Semantic proximity Read ↗

Molecular genetics of the Drosophila melanogaster ovo locus, a gene required for sex determination of germline cells.Semantic proximity Read ↗

Genetic and molecular characterization of P element-induced mutations reveals that the Drosophila ovarian tumor gene has maternal activity and a variable null phenotype.Semantic proximity Read ↗

Sex determination of germ cells in Drosophila.Semantic proximity Read ↗

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