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Article

Markers on distal chromosome 2q linked to insulin-dependent diabetes mellitus.

Science (New York, N.Y.) - 21 Jun 1996

Morahan G, Huang D, Tait B D, Colman P G, Harrison L C

Abstract excerpt

Insulin-dependent diabetes mellitus (IDDM) is a multigenic autoimmune disease. An IDDM susceptibility gene was mapped to chromosome 2q34. This gene may act early in diabetogenesis, because "preclinical" individuals also showed linkage. Human leukocyte antigen (HLA)-disparate, but not HLA-identical, sibs showed linkage, which was even stronger in families with affected females. The genes encoding insulin-like...

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Identifiers

PMID: 8650584
DOI: 10.1126/science.272.5269.1811

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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