Article
Compound evolutionary history of the rhesus macaque MHC class I B region revealed by microsatellite analysis and localization of retroviral sequences.
PloS one - 1 Jan 2009
Doxiadis Gaby G M, Heijmans Corrine M C, Bonhomme Maxime, Otting Nel, Crouau-Roy Brigitte, Bontrop Ronald E
Abstract excerpt
In humans, the single polymorphic B locus of the major histocompatibility complex is linked to the microsatellite MIB. In rhesus macaques, however, haplotypes are characterized by the presence of unique combinations of multiple B genes, which may display different levels of polymorphism. The aim of the study was to shed light on the evolutionary history of this highly complex region. First, the robustness of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
