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Comparative genomics of the human, macaque and mouse major histocompatibility complex.

Immunology - 1 Feb 2017

Shiina Takashi, Blancher Antoine, Inoko Hidetoshi, Kulski Jerzy K

Abstract excerpt

The MHC is a highly polymorphic genomic region that encodes the transplantation and immune regulatory molecules. It receives special attention for genetic investigation because of its important role in the regulation of innate and adaptive immune responses and its strong association with numerous infectious and/or autoimmune diseases. The MHC locus was first discovered in the mouse and for the past 50 years it...

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Identifiers

PMID: 27395034
DOI: 10.1111/imm.12624
PMCID: PMC5214800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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