Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Using buried water molecules to explore the energy landscape of proteins.

Nature structural biology - 1 Jun 1996

Denisov V P, Peters J, Hörlein H D, Halle B

Abstract excerpt

Buried water molecules constitute a highly conserved, integral part of nearly all known protein structures. Such water molecules exchange with external solvent as a result of protein conformational fluctuations. We report here the results of water (17)O and (2)H magnetic relaxation dispersion mea...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aprotinin
Share to Energy Transfer
Share to Magnetic Resonance Spectroscopy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Molecular

Share to Mutation

Share to Protein Conformation

Share to Temperature

Source

Identifiers

PMID: 8646535
DOI: 10.1038/nsb0696-505

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-8646535-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Using buried water molecules to explore the energy landscape of proteins.PMID 8646535Read ↗

Accelerated exchange of a buried water molecule in selectively disulfide-reduced bovine pancreatic trypsin inhibitor.Semantic proximity Read ↗

Water's Variable Role in Protein Stability Uncovered by Liquid-Observed Vapor Exchange NMR.Semantic proximity Read ↗

Probing water micro-solvation in proteins by water catalysed proton-transfer tautomerism.Semantic proximity Read ↗

Prion and water: tight and dynamical hydration sites have a key role in structural stability.Semantic proximity Read ↗

Water-mediated biomolecular dynamics and allostery.Semantic proximity Read ↗

BenchIDPs: Evaluation of Conformational Preferences Molecular Mechanics and Solvent Interactions of IDPs across popular Force Fields and Water ModelsSemantic proximity Read ↗

Statistical and molecular dynamics studies of buried waters in globular proteins.Semantic proximity Read ↗

On the coupling between the dynamics of protein and water.Semantic proximity Read ↗

Analysis of a water mediated protein-protein interactions within RNase T1.Semantic proximity Read ↗

Mapping hydration dynamics around a protein surface.Semantic proximity Read ↗

Hydration free energies and entropies for water in protein interiors.Semantic proximity Read ↗

Water network chemistry to exploit the nature of catalytic water molecules in Mtb DNA gyrase: a computational study to understand the binding mechanism of fluoroquinolones.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.