Article
A novel type of programmed neuronal death in the cervical spinal cord of the chick embryo.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jun 1996
Yaginuma H, Tomita M, Takashita N, McKay S E, Cardwell C, Yin Q W, Oppenheim R W
Abstract excerpt
We examined the massive early cell death that occurs in the ventral horn of the cervical spinal cord of the chick embryo between embryonic days 4 and 5 (E4 and E5). Studies with immunohistochemical, in situ hybridization, and retrograde-tracing methods revealed that many dying cells express Islet proteins and Lim-3 mRNA (motoneuron markers) and send their axons to the somatic region of the embryo before cell...
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