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Article

Expression of MRP and mdr1 in human gastrointestinal cancer cell lines: a correlation with resistance against doxorubicin.

Journal of surgical oncology - 1 Mar 1996

Murase M, Kodera Y, Kondo K, Sekiguchi H, Fujiwara M, Kasai Y, Akiyama S, Ito K, Takagi H

Abstract excerpt

The mRNA expression of mdr1 and MRP, each of which codes for a transport protein belonging to ATP-binding cassette superfamily and are reported to be responsible for multidrug resistance phenotype, were semi-quantified by RT-PCR in a panel of gastrointestinal cancer cell lines. Although the expression of MRP was predominant in esophageal cancer cell lines, expression of either or both of the genes was detected in...

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Identifiers

PMID: 8637212
DOI: 10.1002/(SICI)1096-9098(199603)61:3<223::AID-JSO12>3.0.CO;2-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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