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Multidrug resistance in gastric cancer: recent research advances and ongoing therapeutic challenges

1 Oct 2007

Abstract excerpt

Gastric cancer is the second leading cause of cancer mortality worldwide. The major cause of treatment failure for gastric cancer is the development of multidrug resistance (MDR) to chemotherapy, which is currently one of the primary treatment options. Recently, research into the MDR of gastric cancer has revealed that, in addition to the classical ATP-binding cassette transporters, such as P-glycoprotein (P-gp)...

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PMID: 17944563
DOI: 10.1586/14737140.7.10.1369

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