Article
Increased LRP mRNA expression is associated with the MDR phenotype in intrinsically resistant human cancer cell lines.
International journal of cancer - 17 Sept 1997
Laurençot C M, Scheffer G L, Scheper R J, Shoemaker R H
Abstract excerpt
Multidrug resistance (MDR) in human cancer cells is multifactorial. Previously, we reported on the association between expression of P-glycoprotein (Pgp), the multidrug resistance-associated protein (MRP), and the lung resistance protein (LRP) with the MDR phenotype in the NCI panel of 60 human cancer cell lines used for in vitro anticancer drug screening. Eight cell lines from this panel, manifesting widely...
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