Article
Electron microscopic evidence of impaired intramembrane particles and instability of the cytoskeletal network in band 4.2 deficiency in human red cells.
Cell motility and the cytoskeleton - 1 Jan 1996
Yawata Y, Yawata A, Kanzaki A, Inoue T, Okamoto N, Uehira K, Yasunaga M, Nakamura Y
Abstract excerpt
To obtain direct evidence of impaired intramembrane particles (IMPs) and a deranged cytoskeletal network in situ in human red cells of band 4.2 deficiency, electron microscopic studies were performed utilizing the freeze fracture method for IMPs and the quick-freeze deep-etching method for the cytoskeletal network. Three patients with three different previously identified mutations of the band 4.2 gene, i.e.,...
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