Role of hemichrome binding to erythrocyte membrane in the generation of band-3 alterations in beta-thalassemia intermedia erythrocytes.

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Article

Role of hemichrome binding to erythrocyte membrane in the generation of band-3 alterations in beta-thalassemia intermedia erythrocytes.

Blood - 1 Sept 1995

Mannu F, Arese P, Cappellini M D, Fiorelli G, Cappadoro M, Giribaldi G, Turrini F

Abstract excerpt

Nine splenectomized, hematologically well-compensated beta-thalassemia intermedia patients randomly chosen from a pool of 60 similar patients were studied. Membrane proteins solubilized with nondenaturing detergent C12E8 were gel filtered on Sepharose CL-6B (Pharmacia Fine Chemicals, Uppsala, Swe...

Topics

Adolescent
Adult
Anion Exchange Protein 1, Erythrocyte
Chromatography, Gel
Electrophoresis, Polyacrylamide Gel
Erythrocyte Membrane
Female
Genotype
Hemeproteins
Humans
Male
Membrane Proteins
Molecular Weight
beta-Thalassemia

Source

Open in PubMed

Identifiers

PMID: 7655029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7655029-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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