The three-dimensional structure of two mutants of the signal transduction protein CheY suggest its molecular activation mechanism.

doi:10.1006/jmbi.1996.0151

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Article

The three-dimensional structure of two mutants of the signal transduction protein CheY suggest its molecular activation mechanism.

Journal of molecular biology - 22 Mar 1996

Bellsolell L, Cronet P, Majolero M, Serrano L, Coll M

Abstract excerpt

The three-dimensional crystal structures of the single mutant M17G and the triple mutant F14G-S15G-M17G of the response regulator protein CheY have been determined to 2.3 and 1.9 angstrom, respectively. Both mutants bind the essential Mg2+ cation as determined by the changes in stability, but bin...

Topics

Bacterial Proteins
Crystallization
Escherichia coli
Escherichia coli Proteins
Magnesium
Membrane Proteins
Methyl-Accepting Chemotaxis Proteins
Mutation
Protein Conformation
Signal Transduction

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