Article
The Solvation of the E. coli CheY Phosphorylation Site Mapped by XFMS.
International journal of molecular sciences - 23 Oct 2022
Hamid Maham, Khalid Muhammad Farhan, Chaudhary Safee Ullah, Khan Shahid
Abstract excerpt
The Escherichia coli CheY protein belongs to a large bacterial response regulator superfamily. X-ray hydroxy radical foot-printing with mass spectroscopy (XFMS) has shown that allosteric activation of CheY by its motor target triggers a concerted internalization of aromatic sidechains. We reanalyzed the XFMS data to compare polar versus non-polar CheY residue positions. The polar residues around and including the...
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