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Article

Role of Position K+4 in the Phosphorylation and Dephosphorylation Reaction Kinetics of the CheY Response Regulator.

Biochemistry - 6 Jul 2021

Foster Clay A, Silversmith Ruth E, Immormino Robert M, Vass Luke R, Kennedy Emily N, Pazy Yael, Collins Edward J, Bourret Robert B

Abstract excerpt

Two-component signaling is a primary method by which microorganisms interact with their environments. A kinase detects stimuli and modulates autophosphorylation activity. The signal propagates by phosphotransfer from the kinase to a response regulator, eliciting a response. Response regulators operate over a range of time scales, corresponding to their related biological processes. Response regulator active site...

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Identifiers

PMID: 34167303
DOI: 10.1021/acs.biochem.1c00246
PMCID: PMC8476072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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