Article
The Pichia pastoris PER6 gene product is a peroxisomal integral membrane protein essential for peroxisome biogenesis and has sequence similarity to the Zellweger syndrome protein PAF-1.
Molecular and cellular biology - 1 May 1996
Waterham H R, de Vries Y, Russel K A, Xie W, Veenhuis M, Cregg J M
Abstract excerpt
We report the cloning of PER6, a gene essential for peroxisome biogenesis in the methylotrophic yeast Pichia pastoris. The PER6 sequence predicts that its product Per6p is a 52-kDa polypeptide with the cysteine-rich C3HC4 motif. Per6p has significant overall sequence similarity with the human peroxisome assembly factor PAF-1, a protein that is defective in certain patients suffering from the peroxisomal disorder...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.