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Article

Simian immunodeficiency virus RNA is efficiently encapsidated by human immunodeficiency virus type 1 particles

1 May 1993

Abstract excerpt

Packaging of retroviral RNA is attained through the specific recognition of a cis-acting encapsidation site (located near the 5' end of the viral RNA) by components of the Gag precursor protein. Human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) are two lentiviruses that lack apparent sequence similarity in their putative encapsidation regions. We used SIV vectors to determine...

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PMID: 8474168
DOI: 10.1128/jvi.67.5.2681-2688.1993

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