Article
Phenotypic properties of herpes simplex virus 1 containing a derepressed open reading frame P gene.
Journal of virology - 1 Mar 1996
Lagunoff M, Randall G, Roizman B
Abstract excerpt
Open reading frame P (ORF P) maps in the viral DNA sequences transcribed during latency and is located antisense to the gamma 1 34.5 gene. Earlier studies have shown that the expression of ORF P is repressed by an infected cell protein no. 4 binding site straddling the transcription initiation site. We have made monospecific polyclonal antibodies to the protein and constructed a virus, designated ORF P++, in...
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