Article
Widespread microsatellite instability occurs infrequently in adenocarcinoma of the gastric cardia.
Oncogene - 18 Apr 1996
Gleeson C M, Sloan J M, McGuigan J A, Ritchie A J, Weber J L, Russell S E
Abstract excerpt
Heredity non-polyposis colorectal cancer (HNPCC) is associated with an increased predisposition to colorectal cancer and extra-colonic cancers of the gastro-intestinal, urological and female reproductive tracts. These tumours are characterised by an underlying defect in DNA mismatch repair and exhibit numerous replication errors throughout the genome (RER+ phenotype). HNPCC-associated gastric tumours, and a...
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