Article
Inhibition of v-Mos kinase activity by protein kinase A.
Molecular and cellular biology - 1 Mar 1996
Yang Y, Herrmann C H, Arlinghaus R B, Singh B
Abstract excerpt
We investigated the effect of cyclic AMP-dependent protein kinase (PKA ) on v-Mos kinase activity. Increase in PKA activity in vivo brought about either by forskolin treatment or by overexpression of PKA catalytic subunit resulted in a significant inhibition of v-Mos kinase activity. The purified PKA catalytic subunit was able to phosphorylate recombinant p37v-mos in vitro, suggesting that the mechanism of in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
