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Article

Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression.

Molecular and cellular biology - 1 Mar 1996

Bennett A M, Hausdorff S F, O'Reilly A M, Freeman R M, Neel B G

Abstract excerpt

Using transient overexpression and microinjection approaches, we examined SHPTP2's function in growth factor signaling. Overexpression of catalytically inactive SHPTP2 (PTP2CS) but not catalytically inactive SHPTP1, inhibited mitogen-activated protein (MAP) kinase activation and Elk-1 transactivation following epidermal growth factor (EGF) stimulation of 293 cells. An SHPTP2 mutant with both C-terminal tyrosyl...

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Identifiers

PMID: 8622663
DOI: 10.1128/MCB.16.3.1189
PMCID: PMC231101

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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