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Exposure of pregnant mice to carbon black by intratracheal instillation: Toxicogenomic effects in dams and offspring

12 Oct 2011

Abstract excerpt

Exposure to nanomaterials (NM) during sensitive developmental stages may predispose organisms to diseases later in life. However, direct translocation of NM from mother to fetus through the placenta is limited. The present study tests the hypothesis that pulmonary exposure to NM and NM-induced response, such as inflammation during gestation, leads to secondary effects in the fetus. Time-mated C57BL/6BomTac mice...

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Identifiers

PMID: 22001195
DOI: 10.1016/j.mrgentox.2011.09.018

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