Article
Cell density control of staphylococcal virulence mediated by an octapeptide pheromone.
Proceedings of the National Academy of Sciences of the United States of America - 19 Dec 1995
Ji G, Beavis R C, Novick R P
Abstract excerpt
Some bacterial pathogens elaborate and secrete virulence factors in response to environmental signals, others in response to a specific host product, and still others in response to no discernible cue. In this study, we have demonstrated that the synthesis of Staphylococcus aureus virulence factors is controlled by a density-sensing system that utilizes an octapeptide produced by the organism itself. The...
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