Article
Experimental transmission of Creutzfeldt-Jakob disease and related diseases to rodents.
Neurology - 1 Feb 1996
Tateishi J, Kitamoto T, Hoque M Z, Furukawa H
Abstract excerpt
Sporadic Creutzfeldt-Jakob disease (CJD) with 129M/M, and iatrogenic and familial CJD with E200K and M232R, showed similar clinicopathologic features, a synaptic type deposition of PrPCJD, and high transmission frequencies to mice. Sporadic patients with 129M/V or 129V/V, and mutation cases with V180I, showed slightly different features and low or null transmission frequencies to mice. Hereditary cases with...
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