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Article

Limited transmission of V180I genetic Creutzfeldt-Jakob disease in knock-in mice models.

The Journal of general virology - 1 Mar 2026

Teruya Kenta, Mohri Shirou, Kitamoto Tetsuyuki

Abstract excerpt

Differentiating Creutzfeldt-Jakob disease (CJD) with the V180I mutation from other types of dementia is extremely difficult. Additionally, its differentiation is sometimes determined after performing neurosurgery, which is associated with a high risk of V180I prion contamination; however, the infectivity of the V180I prion has not been properly investigated. Especially in East Asia, this issue must be addressed...

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Identifiers

PMID: 41849197
DOI: 10.1099/jgv.0.002224
PMCID: PMC12999274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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