Article
Evolutionary conservation of RecA genes in relation to protein structure and function.
Journal of bacteriology - 1 Apr 1996
Karlin S, Brocchieri L
Abstract excerpt
Functional and structural regions inferred from the Escherichia coli R ecA protein crystal structure and mutation studies are evaluated in terms of evolutionary conservation across 63 RecA eubacterial sequences. Two paramount segments invariant in specific amino acids correspond to the ATP-binding A site and the functionally unassigned segment from residues 145 to 149 immediately carboxyl to the ATP hydrolysis B...
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