Article
Expression of bcl-x during mouse B cell differentiation and following activation by various stimuli.
European journal of immunology - 1 Mar 1996
Choi M S, Holmann M, Atkins C J, Klaus G G
Abstract excerpt
We have studied the expression of the novel anti-apoptotic protein bcl-x during mouse B cell differentiation and activation. We find that bcl-x is expressed throughout all stages of B cell differentiation in the bone marrow, and is only down-regulated in mature (sIgD+) B cells. Immature peripheral B cells express low levels of bcl-x even in adult animals, whereas mature resting B cells do not. Mature B cells...
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