Allelic imbalance in the region of the BRCA1 gene in ductal carcinoma in situ of the breast.

doi:10.1038/bjc.1996.110

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Article

Allelic imbalance in the region of the BRCA1 gene in ductal carcinoma in situ of the breast.

British journal of cancer - 1 Mar 1996

Munn K E, Walker R A, Menasce L, Varley J M

Abstract excerpt

Thirty-four cases of ductal carcinoma in situ (DCIS) of the breast, with or without associated benign or invasive disease, were analysed for allelic imbalance (AI) in the region of the BRCA1 gene. AI on 17q12-23 in DCIS was demonstrated in 74% of cases, and in the majority of cases the region of...

Topics

Alleles
BRCA1 Protein
Breast Neoplasms
Carcinoma in Situ
Carcinoma, Ductal, Breast
Chromosomes, Human, Pair 17
Female
Genes, erbB-2
Humans
Neoplasm Proteins
Transcription Factors

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