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Article

Allelic imbalance in the region of the BRCA1 gene in ductal carcinoma in situ of the breast.

British journal of cancer - 1 Mar 1996

Munn K E, Walker R A, Menasce L, Varley J M

Abstract excerpt

Thirty-four cases of ductal carcinoma in situ (DCIS) of the breast, with or without associated benign or invasive disease, were analysed for allelic imbalance (AI) in the region of the BRCA1 gene. AI on 17q12-23 in DCIS was demonstrated in 74% of cases, and in the majority of cases the region of AI included the BRCA1 gene. However, two cases showed AI distal to BRCA1, supporting the presence of a second...

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Source

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Identifiers

PMID: 8605099
DOI: 10.1038/bjc.1996.110
PMCID: PMC2074329

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Allelic imbalance in the region of the BRCA1 gene in ductal carcinoma in situ of the breast.PMID 8605099Read ↗

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Detection of allelic imbalance indicates that a proportion of mammary hyperplasia of usual type are clonal, neoplastic proliferations.Semantic proximity Read ↗

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