Article
Detection of allelic imbalance indicates that a proportion of mammary hyperplasia of usual type are clonal, neoplastic proliferations.
Laboratory investigation; a journal of technical methods and pathology - 1 Jan 1996
Lakhani S R, Slack D N, Hamoudi R A, Collins N, Stratton M R, Sloane J P
Abstract excerpt
Previously, we developed methodology for studying allelic imbalance (AI) in preinvasive breast disease and showed that AI identified at various chromosomal loci in invasive carcinoma is already present in in situ carcinoma and atypical hyperplasia. We now extend this work by looking for Ai in hyp...
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