Autophagic death after cell cycle arrest at the restrictive temperature in temperature-sensitive cell division cycle and secretory mutants of the yeast Saccharomyces cerevisiae.

Abstract excerpt

When virgin temperature-sensitive mutant cdc28 cells of the yeast Saccharomyces cerevisiae were incubated at restrictive temperatures, they continued to grow, reaching a maximum of 3.3-fold the original size after 24 h. The protein and RNA levels increased during the first 24 h, then gradually de...

Topics

• Autophagy
• CDC28 Protein Kinase, S cerevisiae
• Cell Cycle
• Cell Cycle Proteins
• Cell Division
• DNA, Fungal
• Fungal Proteins
• Hydrolases
• Mutation
• RNA, Fungal
• Saccharomyces cerevisiae
• Temperature
• Vacuoles