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Article

An ARL1 mutation affected autophagic cell death in yeast, causing a defect in central vacuole formation.

Cell death and differentiation - 1 Feb 2002

Abudugupur A, Mitsui K, Yokota S, Tsurugi K

Abstract excerpt

When the cdc28 strain of Saccharomyces cerevisiae is incubated at restrictive temperatures, the yeasts digest themselves in 7 days by activating autophagic machinery. In parallel, the cell-proliferative activity decreases progressively after about 48 h. We have previously referred to this phenomenon as autophagic death. In the present study, we isolated and characterized a recessive mutant strain, dlp2, which...

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Source

Identifiers

PMID: 11840166
DOI: 10.1038/sj.cdd.4400942

Genes

ARL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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