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Article

Arg506-Gln mutation in factor V and risk of thrombosis during pregnancy.

British journal of haematology - 1 Feb 1996

Bokarewa M I, Bremme K, Blombäck M

Abstract excerpt

Seventy women with thrombosis in pregnancy were investigated for the presence of APC resistance and the associated Arg506-Gln mutation in coagulation factor V. The mutation was found in 46% of the investigated women. Carriers of the mutation were more prone to develop thrombosis in the first pregnancy (OR (odds ratio) = 3.41; P < 0.05) and had a higher probability of recurrence (OR = 3.86; P < 0.05) compared to...

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Source

Identifiers

PMID: 8603019
DOI: 10.1046/j.1365-2141.1996.d01-1496.x

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Arg506-Gln mutation in factor V and risk of thrombosis during pregnancy.PMID 8603019Read ↗

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Resistance to activated protein C caused by a factor V gene mutation.Semantic proximity Read ↗

Identification of the same factor V gene mutation in 47 out of 50 thrombosis-prone families with inherited resistance to activated protein C.Semantic proximity Read ↗

Resistance to activated protein C caused by the R506Q mutation in the gene for factor V is a common risk factor for venous thrombosis.Semantic proximity Read ↗

Early days of APC resistance and FV Leiden.Semantic proximity Read ↗

Activated protein C resistance due to a common factor V gene mutation is a major risk factor for venous thrombosis.Semantic proximity Read ↗

Co-segregation of thrombosis with the factor V Q506 mutation in an extended family with resistance to activated protein C.Semantic proximity Read ↗

Factor V Leiden (R506Q) and risk of venous thromboembolism: a case-control study based on the Spanish population.Semantic proximity Read ↗

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Inherited resistance to activated protein C caused by presence of the FV:Q506 allele as a basis of venous thrombosis.Semantic proximity Read ↗

Predisposition to thrombosis by a factor V mutation causing hereditary resistance to activated protein C.Semantic proximity Read ↗

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