Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multi-faceted analyses of a highly metastatic human lung cancer cell line NCI-H460-LNM35 suggest mimicry of inflammatory cells in metastasis.

Oncogene - 12 Jul 2001

Kozaki K, Koshikawa K, Tatematsu Y, Miyaishi O, Saito H, Hida T, Osada H, Takahashi T

Abstract excerpt

This study established and characterized low-metastatic revertant and parental clones of a highly metastatic human lung cancer cell line, NCI-H460-LNM35 (hereafter referred to as LNM35). Expression-profiling analysis revealed that up-regulation of various proinflammatory cytokines and angiogenic chemotactic chemokines was present in LNM35. Further, while COX-2 itself is known to be inducible in inflammation,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclooxygenase 2
Share to Isoenzymes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Nude

Share to Mice, SCID

Share to Neoplasm Metastasis

Share to Oligonucleotide Array Sequence Analysis

Share to Prostaglandin-Endoperoxide Synthases

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 11464289
DOI: 10.1038/sj.onc.1204561

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multi-faceted analyses of a highly metastatic human lung cancer cell line NCI-H460-LNM35 suggest mimicry of inflammatory cells in metastasis.PMID 11464289Read ↗

Promotion of a cancer-like phenotype, through chronic exposure to inflammatory cytokines and hypoxia in a bronchial epithelial cell line model.Semantic proximity Read ↗

Increased expression of COX-2 in the development of human lung cancers.Semantic proximity Read ↗

Establishment of a human lung cancer cell line with high metastatic potential to multiple organs: Gene expression associated with metastatic potential in human lung cancerSemantic proximity Read ↗

Gene Expression Profiling Reveals Cross-talk between Melanoma and Fibroblasts: Implications for Host-Tumor Interactions in MetastasisSemantic proximity Read ↗

Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via VEGF-C.Semantic proximity Read ↗

ERK5 mediates pro-tumorigenic phenotype in non-small lung cancer cells induced by PGE2.Semantic proximity Read ↗

CCR1 knockdown suppresses human non-small cell lung cancer cell invasion.Semantic proximity Read ↗

The Effects of 2,2',4'-Trihydroxychalcone on the Cell Proliferation, Metastasis, and Apoptosis in Human Lung Cancer Cell Line A549Semantic proximity Read ↗

Analysis of tumor-host interactions by gene expression profiling of lung adenocarcinoma xenografts identifies genes involved in tumor formation.Semantic proximity Read ↗

Spontaneous lung metastases in a human lung tumor xenograft: a new experimental model.Semantic proximity Read ↗

Inflammation-mediated promotion of invasion and metastasisSemantic proximity Read ↗

Profiling the evolution of human metastatic bladder cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.